Our Commitment

We support entrepreneurs and start-up companies in the life sciences to grow and market new ideas.

Smile’s cost-effective, quality-oriented and market-focused solutions for early phase life science companies are focused on creating a greater base of successful and sustainable life science companies in the region.

A Unique Position at Medicon Village

The facilities at Medicon Village provide an excellent base for expansion to a greater critical mass of companies that can benefit from shared competencies and access to a wide variety of advanced instrumentation. We actively work to grow a valuable portfolio of companies in various life science branches and development stages to stimulate a rewarding exchange of experiences and knowledge between companies.

An exclusive offer
Smile Incubator offers guidance and support during the first key years of business, when the need for risk management is highest. The incubator program includes business development support for business concepts, management teams and companies. Participation in the incubator is fee based, and incubator support offered to companies is subsidized by public and private sponsors.
A Creative Environment
Smile’s creative environment provides excellent conditions for the development of startup companies in life sciences. If needed, we offer guidance and training on both operation of various instruments and management of various regulations.
Individual Laboratories, Offices and Specialty Storage
At Smile companies can have individual laboratory space, offices and storage, as needed, with the ability to expand as the company grows. We also have specialty storage for chemicals and solvents.
Maker Spaces (Shared Laboratories) with Advanced Instrumentation
In the incubator’s core facility, companies have access to a large number of instruments for most applications in life science. The incubator and incubator companies together represent very broad expertise in life science and offer training, support and the opportunity to purchase expert and research services when necessary.

The Incubator

Business development and leadership

The incubator management team coaches and provides decision-making support to you in business development and management matters to help attain the best results for your company. We work with qualified partners in areas including business intelligence, intellectual property, law and finance to provide several standard products as well as solutions tailored to the respective business needs. We also organize information and training sessions to provide you the opportunity for personal professional development.

Facilities

Individual laboratories 1700 m²

Individual offices 750 m²

Storage 400 m²

Core facility 300 m²

Shared common areas 1730 m²

Total area of Smile 4880 m²

Conference/Meeting

We have several conference rooms with projector equipment and small meeting rooms which one may use at no extra charge.

Core Facility Equipment

Balances

Laboratory balance
Mettler Toledo, PR2002, Resolution 10 mg, Max weight 2100 g. Balance useful when measuring buffer salts and reagents in gram quantities.

Analytical balance
Mettler Toledo, AT261, Resolution 0.01 mg, Max weight 62 g. Balance for high precision measurements of active ingredients.

Micro balance
Mettler Toledo, MT5, Resolution 0.001 mg, Max Weight 5 g. Balance with extremely high precision and therefore limited maximum weight.

Cell culturing lab

Laboratory for established cell lines.

3 CO₂ incubators for cell culturing
3 Laminar Flow Benches
Microscope
Centrifuge for tubes and plates

Cell lab for primary cells

Laboratory for cells derived from living tissue.

2 CO₂ incubators for cell culturing
2 Laminar Flow Benches
Microscope

Centrifuges

Cytospin Centrifuge
Shandon, Cytospin 3

Plate Centrifuge
Sorwall, Legend RT

Tube centrifuge
Heraeus, Multifuge 3 S-R

Eppendorf tube centrifuge
Sigma 1 K 15

Centrifuge High Speed for harvesting cells or other preparative tasks
Beckman Coulter, Avanti J-E with rotor for 50 or 500 ml tubes.

Chromatography

UPLC-PDA, Ultra performance liquid chromatography combined with photo diode array detector.
Waters, Aquity

HPLC-PDA-ELS, High performance liquid chromatography combined with photo diode array and light scattering detector.
Agilent 1100 HPLC modules and Polymer laboratories PL-ELS 2100

HPLC-UV High performance liquid chromatography dual wavelength UV.
Agilent, 1100 HPLC modules.

Protein Chromatography system with fraction collector.
Amersham Pharmacia Biotech, Äkta FPLC with pH, UV and conductivity detection.

Flow Cytometry

Beckman Coulter CytoFLEX
3 lasers and a total of 13 channels
Blue laser 488 nm: 5 channels
Red laser 638 nm: 3 channels
Violet laser 405 nm: 5 channels

Histology

2 Cryostat Microtomes for preparation of slides from frozen tissue
Leica, CM3050 S and Microm, HM 500 OM

Microtome for preparation of slides from paraffin embedded tissue
Microm, HM 360

Tissue Embedding instrument to embed tissue into paraffin blocks
Thermo Fischer, Histostar

Binocular Microscope
Leica, DM 1000

Tissue Processor for dehydration of tissue prior to paraffin embedding
Sakura, Tissue Tech VIP

Liquid handling and automation

Liquid Handling Robot for assay automation
Tecan, Genesis Freedom 150, 8 channels

Liquid Dispenser with 8 channels for microtiter plates
Labsystems, Multidrop 384

Plate Washer with 8 channels for microtiter plates
Mikura

Mass spectrometry

UPLC-PDA-Ion trap MS/MS for qualitative mass spectrometry tasks
Thermo Scientific, Accelera UPLC and LTQ XL mass spectrometer.

HPLC-Quadrupole MS/MS for quantitative mass spectrometry tasks
Shimadzu 10 HPLC and Micromass Quattro Ultima mass spectrometer.

GC-MS for mass spectrometry of volatile compounds
Agilent, 6890N gas chromatograph and 5973 mass selective detector.

Microscopy Confocal

Provided with application expert from SmiLe company

Zeiss LSM800
Inverted high resolution microscope equipped for:
High sensitivity
Multi fluorescence detection
Near infrared detection
Live cell imaging
High content screening

Microscopy Fluorescence

Leica DM Irbe
Inverted Configuration
4 fluorescence filter cubes

Leica DC 500
Straight configuration
3 fluorescence filter cubes

Miscellaneous laboratory equipment

Waterbath 10 litre, Clifton
Waterbath 2 litre, Grant, SUB6
Oven 300 °C, Heraeus, T6060
Oven 70°C, Heraeus, B6
pH meter, Mettler Toledo, FiveEasy
Sample evaporator, ThermoFisher Speedvac SPD 2010
Table Autoclave, Tuttnauer Systec, 2540 EL
Electroporator, Amaxa, Nucleofector 1

Molecular Biology

Conventional PCR in 20 or 96 well configuration
MJ research, PCT 200

Real Time PCR in 96 well configuration
Biorad, C1000 Real time system

Gel electrophoresis equipment for protein and DNA analysis

Gel documentation system
Gene Flash Bio Imaging

Protein production

Incubator cooled shaker
B Braun, Certomat BT-T

Incubator shakers
New brunswick scientific, Innova 4300 and Innova 43

Centrifuge High Speed for harvesting cells or other preparative tasks
Beckman Coulter, Avanti J-E with rotor for 50 or 500 ml tubes

Nanophotometer for UV/Vis spectroscopy in microliter volumes
Implen, P330

Microwave oven
Electrolux

Spectroscopy

UV/Vis spectrophotometer in diode array configuration for fast spectrum acquisition
Agilent, 8453

Nanophotometer for UV/Vis spectroscopy in microliter volumes
Implen, P330

Fourier transformed infrared spectroscopy FT-IR with easy ATR sampling
Perkin Elmer, Spectrum Two

Multimode plate reader with capability of absorption, fluorescence and luminescence measurement in 96 or 384 well plates
Molecular Devices, i3

Fluorescence plate reader with capability of fluorescence polarization
BMG, Polar Star

The incubator process

1. Meet
If your project or company matches the profile to become an incubator company, you will be invited to an initial meeting where we can meet you and learn more about your business.
2. Present
Screening meeting where you can present your business model for a portion of the Smile team.
3. Accept
Following discussion, the team will consider your company’s admission to Smile.
4. Start
Early stage companies or projects accepted to the incubator enter into the incubator’s Start-up Phase or Development Phase and may participate in incubator support for approximately 3 years.
5. Grow
After 3 years most product development companies still have a continued need for the incubator’s infrastructure and have the opportunity to continue as part of the incubator for up to an additional 3 years as a Growth Phase company. Companies may also be accepted directly into the Growth Phase, where appropriate.

Application and admission

Apply to be a member of SmiLe

Every year we accept 8 – 10 new companies into our community. As a member of SmiLe we offer start-ups the following:

Market focus
Business structure
Core facility labs
International finance and industry network
Early business intelligence and market analysis
Customer-driven product development
Expert coaching in Pharma, Med-tech, IP, Marketing, Finance and corporate governance
Education and competence
Early documentation routines and regulatory and IP focus
Community that enables and support development and innovation

What do we require of new entrepreneurs?

To become a member of SmiLe we require that your company has archived the following:

Innovation in Life Science
Registered company
Scalable business idea
International business model
Team
Ambition to grow
Coachable

Coaching

Business development, training, experts & partnering

Capability

Advanced labs and facilities

Community

Collaboration and network with incubator companies & the life science industry

Apply

Who can apply to Lund Smile

We welcome applications from both product companies and service companies within a wide variety of specializations including: Pharmaceutical, Diagnostics, Biotechnology, Medical Technology, Food Technology, Chemistry and Materials, Nano medicine, Digital health and CRO companies.

Application criteria

Applicants must be able to demonstrate a unique idea within the life sciences and a clear market potential. For product development companies, we prefer that the company/ project has begun the process of patenting the idea, where appropriate. For service companies, it is important to show a unique offering, “know how” and a clear customer need. For the company to thrive and reach their goals, the team must also be driven for success.

The Accelerator

Health2B is a lean startup accelerator with a focus on connected health. You may call it digital health, mobile health, e-health, Internet of Things, Wearables, Life Log, Big Data, Bio Hacking or Quantified Self – the goal is the same: to Improve the wellbeing and health of people.

Open Lab Skåne

Use our labs for your research

OpenLab_logotype_RGB_green-grey_R0G177B64_R137G141B141

Are you a company in need of lab space and instrumentation?

Open Lab Skåne is an opportunity for your company to gain access to lab space, state-of-the-art instrumentation and key competences in the field of life science, chemistry and materials science.
We offer custom-made solutions depending on your needs.
For more information visit
OpenLabSkane.se

Contact

THERÉSE NORDSTRÖM
Malmö Högskola, project leader for Open Lab Skåne
Email: therese.nordstrom@mah.se, mobile: +46 (0)70 362 52 08

PER BRUNMARK
SmiLe Incubator, contact person life science,
Email: per@smileincubator.life, mobile: +46 (0)76 850 44 27